There is frequently a family history with autosomal dominant inheritance i e. Blue rubber bleb nevus syndrome is a rare disorder that consists mainly of abnormal blood vessels affecting the skin or internal organs usually the gastrointestinal tract. Blue rubber bleb nevus syndrome brbns or bean syndrome is a rare sporadic syndrome characterized by multifocal venous anomalies patients often have multiple soft blue skin lesions blueberry muffin syndrome associated with multiple bowel venous malformations which could lead to lower gastrointestinal bleeding.
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